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If youve just discovered youre pregnant while still taking a GLP-1, take a deep breath, youre not alone, and theres a clear path forward

Third, the optimal positioning and sequencing of GLP-1-based therapies relative to resmetirom and other emerging MASH agents (e.g., lanifibranor, pegozafermin, semaglutide combination regimens) requires dedicated combination trials, of which preliminary data from the MAESTRO-NASH secondary analysis are encouraging

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Regarding serious renal events, although the combination showed a lower incidence (1.4 vs 2.0 events per 1000 person-years), the confidence interval was wide (HR 0.67