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Phytoene and phytofluene are two main carotenoids present in not only tomatoes but also most plants

doi:10.3389/fendo.2019.00388

The researchers showed that blocking glutamine metabolism through JHU083 not only suppressed tumor cell metabolism but also mitigated the tumor microenvironment, which is hostile to the immune response due to its hypoxic, acidic, and nutrient-depleted conditions, unleashing the natural antitumor T cell response