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Animal experiments in this study were performed in accordance with Yokohama City University Institutional Animal Care and Use Committee guidelines and with ARRIVE guidelines ( All animal experiments were approved by the Institutional Committee of Laboratory Animal Experimentation (Animal Research Center of Yokohama City University, Yokohama, Japan)

Xenobiotics may be detoxified in conjugation reactions with glutathione catalyzed by glutathione S-transferase, which activity is constitutive

Research from Umm Al-Qura University emphasizes the cardioprotective benefits of GLP-1 receptor agonists, along with their low risk of causing hypoglycemia, underscoring their value in a well-rounded approach to reducing cardiovascular disease

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