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People familiar with basal insulins in T2D will be very familiar with such simple, but highly effective, dose titration algorithms (note: insulin glargine, which uses a simple dose titration algorithm, has amassed over $70 billion in sales because it personalises the dose like this

In case of insomnia, try taking this combination in the morning or early afternoon instead of closer to bedtime

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Shifting your schedule repeatedly confuses your body's adaptation to the medication and makes it harder to identify whether side effects are from your current dose or from the timing disruption itself