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These effects were partly attributed to the modulation of the gut microbiota and short-chain fatty acid levels, indicating a potential role in diabetes therapy (385)

Kidney Health & Beyond: Beyond the heart and brain, GLP-1s are being investigated for their potential to reduce the risk of kidney injury

Summary: Retatrutide affects three receptors: the GLP-1 receptor (GLP-1R), the GIP receptor (GIPR), and the glucagon receptor (GCGR), making it an investigational triple receptor agonist