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Health care practitioners prescribe NAC either orally (1330 mg/kg of body weight, given over 72 hours) or intravenously (300 mg/kg of body weight, given over 20 hours) (Amar 2007)

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Based on the estimated 3.8 million Part D enrollees eligible for the Medicare GLP-1 Bridge as of 2023, if 10% to 25% participate in Bridge from when the program launches in July 2026 and fill a prescription each month for the 18-month duration of the program, the cost to Medicare would be $1.3 billion to $3.3 billion (at a net monthly cost of $245 minus the $50 beneficiary copay)