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GHK-Cu Peptide & Barrier Integrity (Preclinical Research) In a mouse model of DSS-induced ulcerative colitis, researchers observed that GHK-Cu influenced cellular signaling pathways related to barrier integrity, including: Tight junction protein expression SIRT1/STAT3 signaling pathways While this study was preclinical and not cosmetic-focused, it reinforced something researchers have long suspected: GHK-Cu interacts with fundamental cellular repair processes, not just surface-level skin processes [1]
Minimal response may warrant increasing by 50-100mcg
Myostatin (1) Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S
Separately, RegeneRx's ophthalmic formulation RGN-259 completed Phase 3 trials (ARISE-1 and ARISE-2) for dry eye with mixed results
![PDF] Catalase and glutathione peroxidase are equally active in detoxification of hydrogen peroxide in human erythrocytes](https://figures.semanticscholar.org/e57b719abf8498181e0be7902735507a49da0e4f/2-Figure1-1.png)
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