In the UK, there are specific NHS criteria: Semaglutide 2.4mg (Wegovy) : NICE technology appraisal TA875 recommends this only within specialist weight management services and for a maximum of 2 years on the NHS [2] Liraglutide 3.0mg (Saxenda) : NICE technology appraisal TA664 specifies that treatment should only continue beyond 12 weeks if you've lost at least 5% of your initial body weight Clinical trials have demonstrated that most people regain weight after stopping GLP-1 medications
DIRKO, Double incretin receptor knockout
The study, presented at this years European Congress on Obesity in Malaga, Spain (11-14 May) and published in NEJM , is by Dr Louis J Aronne, Director of the Comprehensive Weight Control Center at Weill Cornell Medicine, New York, New York, USA, and colleagues
DOI: 10.1002/mnfr.202100071 Liu, D., Alkhalidy, H., et al