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SURMOUNT-1 Tirzepatide The pivotal tirzepatide trial, published in the New England Journal of Medicine in 2022, randomized 2,539 adults with obesity to tirzepatide 5 mg, 10 mg, 15 mg or placebo for 72 weeks
TIRZEPATIDE For research use only
If you are combining semaglutide with phentermine , berberine , or metformin , these additional medications can further affect appetite and blood sugar, making calorie monitoring even more important
Other Medical Considerations Fatigue may also be related to labeled risks such as gallbladder disease or pancreatitis, which can present with malaise along with abdominal pain
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