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Commenters stated that the current report lacks sufficient granularity and consistency for manufacturers to independently validate refund calculations, creating compliance risks and administrative burdens

The GLP-1 receptor is widely expressed throughout the hypothalamus, with the highest expression in the PVN and ARC (60, 61)

The AML xenograft model was established by abdominal method, with 1 10 6 HL60 cells intraperitoneally injected in Balb/c nude mice

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