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Tissue-Specific Accumulation : Research indicates this form preferentially accumulates in metabolically active tissues like the brain, liver, and lungs, where glutathione demand is highest for maintaining cellular function
In contrast to TMAO, betaine exhibits beneficial effects on human health, it could be used as a promising preventive therapy for liver disease, cardiovascular disease, neurodegenerative disease, etc
5.3 Other emerging strategies to target the LPA axis Beyond ATX/LPAR inhibition, other LPA-targeting strategies have emerged, including neutralizing extracellular LPA, blocking alternative LPA-producing enzymes, and enhancing LPA degradation
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