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863 NCOA4 mediated ferritinophagy plays a crucial role in regulating intracellular iron levels, and elevated expression of NCOA4 has been observed in the cartilage of OA patients, OA mice, and inflammatory chondrocytes

5.2.1 Key antioxidant pathways in ferroptosis regulation In critical oxidative stress response pathways, Nrf2/HO-1 signaling is paramount, with Nrf2 serving as a key endogenous antioxidant factor

They support your immune system naturally with a high-impact blend of vitamin C, zinc, and glutathione