Thomas Clark is Board Certified in Cardiometabolic Medicine and enjoys seeing patients for diabetes management, kidney disease, liver disease, and other chronic conditions
What to look for: Probiotics that don't add prebiotic fibers (which can increase stomach pressure via gas) Lower CFU options if you're prone to reflux flare-ups Saccharomyces boulardii in some cases, if you're also having loose stools A useful mindset: if reflux is your main problem, prioritize GLP-1-specific behavior strategies (smaller meals, lower-fat meals, not lying down after eating, and discussing medication timing or dose escalation with your prescriber)
Vasodilatory effect Studies showed that GIPR and GLP1R are present in the smooth muscle cells and endothelial arterioles and may have a cardioprotective effect due to endothelium-dependent vasodilation [105]
The LC-MS/MS was performed on both polar and hydrophobic metabolites using an Ultimate 3000 RSLC nano coupled to an HPG pump or a Vanquish Flex UPLCs coupled to Orbitrap Fusion Lumos Tribrid mass spectrometer (Thermo Fisher Scientific) in HILIC LC-MS and RP-LC-MS, operated in positive and negative ionization modes as described previously 30
