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Determination of the melanocortin-4 receptor structure identifies Ca 2+ as a cofactor for ligand binding

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Therefore, a study used dual molecules such as ciprofloxacin (CIP) and an efflux inhibitor 5-Nitro-2-(3-phenylpropoxy) pyridine (5-NPPP) were used to synthesize and deliver together with an antibiotic can re-sensitize pathogen against antibiotics and simultaneously treat the infections

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Another possible way to induce depletion of intracellular cysteine has been proposed by Cramer's group using systemic depletion of cysteine in the plasma of leukemic mice

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