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Observational designs cant prove causality but they do inform riskbenefit discussions

Calkin C, McClelland C, Cairns K, Kamintsky L, Friedman A

TAS, TOS, and OSI levels were not significantly different between migraine patients and controls in some studies (Eren et al., 2015

We then envisioned two further scenarios that could explain the differential Nt 7 compartmentalization: (i) PATs have no specificity for substrate recognition, and substrates concentrate at different compartments due to specific interactions, and (ii) PATs discriminate substrates, which in turn accumulate at the compartment where S-palmitoylation takes place