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Description

After reaching a stable maintenance dose, individuals usually continue the program for at least 6 to 12 months, since meaningful and sustainable weight reduction takes time

Occasional heartburn after spicy meals is normal, but frequent symptoms occurring more than twice weekly may indicate gastroesophageal reflux disease (GERD)

The compound was first characterised and studied by Predrag Sikiri and colleagues at the University of Zagreb beginning in the 1990s