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Drugs that deplete vitamin B2 will also indirectly deplete vitamin B6 because B2 is required to activate B6: Antipsychotics including Aripiprazole (Abilify), Quetiapine (Seroquel), Risperidone (Risperdal), Olanzapine (Zyrexa), Haloperidol (Haldol), Paliperidone (Invega), Ziprasidone (Geodon) Anticonvulsants and Mood Stabilizers, including Phenytoin (Dilantin), carbamazepine (Tegretol), Primidone (Mysoline), Methsuxamide (Elontin), Valproic acid (Depakote), topiramate (Topomax) and Gabapentin (Neurontin) Symptoms of B6 deficiency include weakness, mental confusion, depression , insomnia and severe PMS symptoms