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No significant difference in food intake was observed between treated and control mice in related studies, indicating that its antiobesity effect mainly depends on regulating fat metabolism rather than suppressing appetite - a unique advantage in obesity research

We also have enzymes in the microbiome that do that

Qu et al., 2023

GLP-1 research peptides dominate modern weight loss science because they simultaneously target appetite, gastric emptying, insulin secretion, and energy expenditure through incretin receptors