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5.4 Potential implications of combined therapies on patient outcomes Although direct clinical evidence supporting combined ferroptosis and cuproptosis targeted therapy remains limited, combined ferroptosis- and cuproptosis-targeted strategies may hold potential to improve patient prognosis across multiple biological and clinical dimensions

Genetic polymorphisms in genes encoding matrix metalloproteinases, collagen synthesis enzymes, or inflammatory mediators could theoretically influence GHK-Cu responsiveness, though systematic investigations of pharmacogenetic determinants remain absent from current literature

Normal physiological processes can be affected by abnormal distribution and content of iron in the body [18]

The thing we have to keep in mind when treating b12 deficiency is that often times the symptoms have taken years to manifest and we may not see a noticeable change after 1-2 shots