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The in vivo activity of ALG-055009 was evaluated in a diet induced obesity (DIO) mouse model where male C57BL/6J mice were fed with a high fat diet for 14 weeks, followed by once daily (QD) or twice daily (BID) oral administration of ALG-055009 for 28 days

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Structurally, GSTs are soluble dimeric proteins with each subunit having a molecular mass of approximately 2228 kDa

doi: 10.1016/j.exer.2025.110576 224 ZhanDZhaoJShiQLouJWangW