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The onset of these diseases is often accompanied by abnormalities in mitochondrial energy metabolism, increased oxidative stress, and exacerbated inflammatory responses, further aggravating the pathological processes

Phospholipids are important structural components of cell membranes, and the sphingolipid, sphingomyelin, is a component of the myelin sheath that enhances nerve transmission (29)

This muscle autocrine/paracrine/endocrine effect has various effects