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Wu K, Chen L, Qiu Z, Zhao B, Hou J, Lei S, et al

Although this study was not designed to examine a dose-response relationship between the exposure and the outcome, this finding may indicate a dose-dependent effect

12 In addition, Asp can promote the activation of hypoxia-inducible factor HIF-1 and inflammasome in M1 macrophages and increase the production of Asn and other metabolites