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Adverse Event Reporting Report adverse reactions to the FDA MedWatch Program at 1-800-FDA-1088 or online at www.fda.gov/medwatch

Heres a short list of some of the TB-500 effects observed in racehorses [22]: Increased endurance Increased strength Increased muscle growth Improved flexibility of joints Improved muscle tone These findings cannot be extrapolated to humans, suggesting that further research in this area is warranted

This is not supported, however, by results from the UKPDS, which reported no increase in fatality for patients taking sulfonylurea treatment (1)

It promotes tissue fibrosis by binding to PDGF receptors, while excessive ECM deposition exacerbates vascular lesions and hypoxia, further aggravating fibrosis (162, 164, 165)