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J Cell Physiol 234(4):41794190 He C, Hart PC, Germain D, Bonini MG (2016) SOD2 and the mitochondrial UPR: partners regulating cellular phenotypic transitions

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Small red bumps called papules and pimple-like pustules frequently occur

This interpretation is consistent with clinical observations that some symptoms diminish or resolve over time, suggesting that in a substantial proportion of patients they may reflect a reversible adaptive process