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This shift not only allows for rapid production of energy but also for maintenance of NADH/NAD + redox ratio, which is required for metabolic processes, such as aerobic glycolysis, the TCA cycle, OXPHOS, FAO, serine biosynthesis and antioxidant defense

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Although the primary focus of our study was on patients with overweight or obesity, approximately 29% of the cohort also had T2D, a significant subgroup due to the well-established link between T2D, psychiatric disorders, and obesity