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Gastric emptying Semaglutide caused a minor delay of early postprandial gastric emptying, thereby reducing the rate at which glucose appears in the circulation postprandially Body weight and constitution Greater weight loss was observed with semaglutide compared to other studied comparators (placebo, sitagliptin, extended release exenatide, dulaglutide and insulin glargine) (see Clinical Efficacy and Safety)

Dr Alison Cave, the MHRA chief safety officer, said: The risk of Naion in patients prescribed semaglutide is extremely low

reported 32.3% cases of SIH and 18.6% cases of SID among patients without pre-existing diabetes (22)