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Melanosomal damage in normal human melanocytes induced by UVB and metal uptakea basis for the pro-oxidant state of melanoma.Photochemistry and Photobiology

Readers comparing routes should ask which endpoints were measured and how long follow-up lasted

Thus, the formation of the dehydro-alanine glutathione species (that observed at m / z 272 in the spectra of glutathione-bound metals) is a key to the possible explanation of the ability of metals such as lead and cadmium to generate oxidative stress in cells without the necessity that the electrochemically silent metal itself change its oxidation state

Hogan AE, Gaoatswe G, Lynch L, Corrigan MA, Woods C, OConnell J, et al