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Crucially, this signaling is bidirectional: central neuroendocrine outputs (e.g., via autonomic nerves and the HPA axis) reciprocally modulate gut physiologyaltering intestinal transit time, mucus secretion, and nutrient availabilitythereby reshaping the microbial metabolic environment and SCFA production capacity

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Then, I follow up with a SNAP-8 product, focusing on areas prone to wrinkles

RT and JP wrote the code and conducted the in silico experiments with HN and MR