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We are excited about this finding, as it shows that the structured intervention improves not only cognition but also other behaviors that affect brain health, which may increase protection against dementia, said Laura D

However, the potential reduction in healthcare resource use across both classes suggests a combination of both SGLT2is and oral GLP-1 RAs may confer long-term cost savings compared to SGLT2is and standard of care alone [32, 33]

This interaction between ghrelin and leptin in control of food intake is called "argentinian ghrelin-leptin tango" ( Fig