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Cardiovascular Outcomes Data Favors Semaglutide For Now The SELECT trial (published in the New England Journal of Medicine in 2023) demonstrated that semaglutide reduced major adverse cardiovascular events by 20% in patients with obesity and established cardiovascular disease
Typical cost: $200 at 2.5 mg weekly, $250 at 5 mg, $300 at 7.5 mg
Clinical data indicate improvements in lipid profiles, blood pressure, and markers of vascular health
Moreover, in subgroup analyses of the controls, tirzepatide did not increase the risks of any of these cancers compared to placebo, insulin, or GLP-1RA (Table 3)
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