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-syn overexpression has been shown to drive microglia polarization towards a pro-inflammatory phenotype, resulting in increased production of inflammatory cytokines such as IL-1, IL-6, and TNF-, as well as enzymes such as COX-2 and iNOS, and the generation of free radicals

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During the manuscript submission process, two other fluorescent probes were independently reported to monitor GSH dynamics in living cells 38,39

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