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The FDA is also warning that many compounded semaglutide products include salt forms (e.g., semaglutide sodium or acetate) that are not used in FDA-approved versions and have not been proven safe or effective

What youll learn: High costs and uncomfortable side effects of traditional GLP-1 medications lead many people to stop using them

In both patient populations with pre-existing cardiovascular disease, DPP-4 inhibitors are recommended as one possible third-line therapy besides SGLT-2 inhibitors, thiazolidinediones, or insulin, when therapeutic goals are not met with the previous dual combination

This approach prevents a double dose, which could increase side effects like nausea or gastrointestinal upset