The imbalance of gut microbiota will reduce the production of SCFAs, weaken the ability to activate SCFAs receptors, and affect GLP-1 secretion, resulting in abnormal glucose metabolism and lipid metabolism (Ma et al., 2019)
Another recent study points out that genetics can influence as much as 50% of a persons propensity to gain weight and difficulty losing it, with the other 50% coming from environmental factors like diet and exercise.2 So, it makes sense that the medical establishment is finally embracing weight loss drugs as more than just a cosmetic concern
Monitoring HbA1c levels is important for managing diabetes because keeping them low not only helps control blood sugar effectively but also reduces the risk of long-term complications like heart disease, nerve damage, kidney problems, and eye issues
References Jastreboff, A.M., Kaplan, L.M., Fras, J.P., Wu, Q., Du, Y., Gurbuz, S., Coskun, T., Haupt, A., Milicevic, Z., & Hartman, M.L