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Before starting treatment, healthcare providers should obtain baseline blood pressure measurements in both sitting and standing positions to identify pre-existing orthostatic hypotension

The loss of SYK signaling interfered with microglial clustering around A plaques, microglial transition into complete DAM phenotype, and phagocytosis of A following exposure to A in 5xFAD mice

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Effect of semaglutide treatment on a proteomic signature of CVD risk A 27-protein score has previously been described that predicts secondary CVD risk over 4 years, based on large multicohort data and using the same SomaScan technology used in our study 22 (Extended Data Table 1)