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Pharmacology of dipeptidyl peptidase-4 inhibitors: Similarities and differences

Previous studies have shown that GLP-1RAs not only modulate the activities of specific neurons within energy metabolism, including PVN, ARC, LH, and NTS of classic homeostasis areas but also influence those of NAc, VTA, cortex in hedonic regions, thereby contributing to energy deficient through reduced food intake, and enhanced energy expenditure, as well as alleviation of the metabolic syndrome

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