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GLS, one of the key enzymes in this pathway, is upregulated in various tumors and is thus considered a potential therapeutic target for cancer

Ethics declarations Competing Interests Authors CWM, OM, SAG and TAT declare that they are employees of Lallemand Health Solutions Inc., a company that researches, manufactures and sells probiotic bacteria to third party companies, not directly to the consumer

However, further prospective cohort studies with clinical endpoints in healthy subjects, and results from on-going randomized, placebo-controlled interventional trials are awaited to truly define the efficiency of homocysteine-lowering therapy in the prevention and correction of vascular disorders among patients with occlusive coronary artery, cerebrovascular and peripheral vascular diseases, and thrombosis related to hyperhomocysteinemia

Its ability to remain chemically intact in gastric conditions facilitates its use via oral, parenteral, or topical administration 2