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Radiographics 37 , 505515 (2017)

The transition often involves a period of reduced efficacy as the body adjusts to the new delivery method and absorption profile

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As US patent exclusivity approaches its 2028 expiration, key dynamics to watch include potential label expansions (such as additional GVHD or inflammatory indications), intensifying competition from next-generation JAK inhibitors and Incytes ability to sustain patient demand while adapting to pricing reforms