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A 12-week facial study on 67 women indicated that GHK-Cu cream applied twice daily improved aged skin appearance, increased thickness, reduced wrinkles and strongly stimulated dermal keratinocyte proliferation as determined by histological analysis of biopsies

[18] The condition manifests as persistent, often asymmetrical swelling that may initially be soft and pitting but progresses to firm, non-pitting oedema as fibrotic changes develop

Journal of Nutritional Science and Vitaminology

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