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The CSF-to-plasma ratio is approximately 0.4%, confirming that a small but definite amount of the drug penetrates the central nervous system (CNS) ( 4 Preclinical evidence: a foundation of neuroprotection The considerable interest in semaglutide as a neurotherapeutic agent is derived from a robust body of preclinical evidence

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Semaglutide is a medication used to treat two main conditions: type 2 diabetes and obesity

Because liraglutide is cleared from the body relatively quickly, you can typically start a new medication without a long waiting period, though your prescriber will advise on timing