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doi: 10.1016/S2213-8587(23)00232-2

56 The most common adverse events were gastrointestinal in the preclinical, phase1 and 2 trials similar to trials involving injectable GLP-1 agonists

The Cureus/PMC study documented both allodynia and dysesthesia in semaglutide and tirzepatide users, suggesting they may represent different points on the same mechanistic spectrum