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Study Groups Four groups were established according to which glucose-lowering agents were prescribed independently of other antidiabetic drugs concurrently prescribed: (a) all GLP-1RA users (GLP-1RA group), (b) SGLT2 inhibitor users with no GLP-1RA prescription (SGLT2i group), (c) insulin users with no GLP-1RA or SGLT2i prescriptions (insulin group) and (d) users of other glucose-lowering agents (miscellany group) (Fig