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Mobilized fatty acids must be oxidized through metabolic activity or exercise rather than re-stored for net fat loss to occur

Acar I, Cetinkaya A, Lay I, Ileri-Gurel E

In line with patient studies, cellular and mouse models of ALS also showed high levels of ROS, along with elevated oxidation of membrane phospholipids (HNE, MDA), DNA (8-OHdG), and proteins (protein carbonyl groups, 3-NT) [94, 109,110,111]