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To put this in perspective, a woman with a waistline of 95 cm (approx 37.4 in) and without underlying health problems or co-morbidities can incur economic costs that are 22%, or US$397, higher per year than a woman with a normal waist circumference

This additive glucose-lowering effect is therapeutically desirable for improving glycaemic control but increases the risk of hypoglycaemia, particularly with glipizide's non-glucose-dependent mechanism

Retatrutide is a more recently developed investigational compound a triple agonist targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously

dipeptidyl peptidase-4 inhibitor use with mortality among patients with type 2 diabetes and advanced chronic kidney disease