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a disease that can develop if strep throat or scarlet fever are not treated properly Collagen vascular diseases , such as lupus, scleroderma or rheumatoid arthritis Pericarditis , a swelling and irritation of the thin saclike membrane surrounding the heart Amyloidosis , the buildup of amyloid proteins in the heart, kidneys, liver or other organs Lyme carditis , a complication of Lyme disease, which occurs when the Lyme-causing bacterium moves to the heart Hypothyroidism affects the heart rate, since the heart rate is regulated by the thyroid hormone Sleep apnea causes sudden drops in blood oxygen levels, which puts a strain on the heart Anorexia nervosa can be a precursor to a lethal heart condition in patients with bradycardia (x) Bradycardia Treatment Borderline or occasional bradycardia may not require treatment

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Changes in NNMT activity may therefore alter the relationship between SAM and S-adenosyl-L-homocysteine and influence methylation-related processes