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Moreover, continued investigation into the pleiotropic effects of GLP-1 receptor agonists may reveal other therapeutic possibilities, possibly transforming the management of many metabolic and non-metabolic disorders

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21 Remarkably, even in HF-free patients with morbid obesity, cardiac abnormalities can be seen that are consistent with left ventricular (LV) remodelling and dysfunction, including greater LV mass, LV diastolic dysfunction and elevated LV filling pressure

Accessed at www.accessdata.fda.gov/drugsatfda_docs/label/2017/209637lbl.pdf on March 13, 2018 102