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used rodent models in vitro and in vivo , besides analyzing human plasma, to demonstrate that desacyl-ghrelin impairs neurogenesis and that the ghrelin: desacyl-ghrelin ratio in circulation is diminished in Parkinsons dementia (43)

Nonsteroidal estrogens of dietary origin: possible roles in hormone-dependent disease

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In one of these studies, older (~67 years), type 2 diabetics, supplemented with 250 mL of beetroot juice (nitrate: 7.5 mmol) for 14 days, experienced a significant improvement in simple reaction time compared to a control group [5]