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134 The NLRP3 is also upregulated resulting from activated NF-B, and activates caspase 1 which induces cell pyroptosis, a type of programmed cell death characterized by the formation of pores in the plasma membrane, leading to the release of proinflammatory cytokines and subsequent cell lysis 38,135 (Fig

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Furthermore, this damage causes a mutation in the DNA molecules regardless of their location, which eventually causes defects in the translated proteins and ultimately impacts multiple facets of cellular physiology [121]

L-Glutathione is discussed here strictly in a research context and is not approved for personal or therapeutic use within this educational protocol