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Description

Older adults, particularly those over 65, sometimes exhibit altered drug metabolism and increased sensitivity to peptide hormones

VAT is a more inflammatory tissue than SAT as it secretes higher levels of proinflammatory cytokines

The body's natural collagen levels eventually decrease with age

instead, they represent a collapse in proteostasis resilience, the intrinsic ability of cells to sense stress, mobilize coordinated responses and restore equilibrium across multiple proteostatic axes