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The findings identified a mechanism distinct from previously known appetite-control pathways as an avenue by which GLP-1s could treat other dysfunctions in reward processing, such as substance use disorder

Baseline serum creatinine and estimated glomerular filtration rate should be documented, with repeat testing if patients experience significant vomiting or diarrhea

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They can help manage metabolic complications associated with Hashimoto's, particularly weight management and insulin resistance, but thyroid hormone replacement therapy remains necessary