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Dosage frequency may vary depending on severity, condition and veterinary advice

eLife 8 , e45572 (2019)

5 However, not all small-molecule GLP-1R agonists have advanced successfully

The maintenance doses used in these trials include: 4 mg once weekly 9 mg once weekly 12 mg once weekly For those taking the maximum 12 mg dose , they follow a gradual increase that looks like this: 2 mg 4 mg 6 mg 9 mg 12 mg (highest dose studied) Each increase happens every 4 weeks , similar to the phase 2 studies, so the full build-up takes about 16 weeks before staying at 12 mg for the rest of the study